- Topical steroids for nasal polyps
Cochrane Systematic Reviews, 25-Apr-2016
Chronic rhinosinusitis with nasal polyps (CRSwNP) represents inflammatory changes throughout the nose and sinuses from a group of disorders which all lead to swelling and overgrowth of the nasal mucosa. Topical corticosteroids have been the most widely us - Topical tacrolimus for atopic dermatitis
Cochrane Systematic Reviews, 1-Jul-2015
Atopic dermatitis (AD) (or atopic eczema) is a chronic inflammatory skin condition that affects children and adults and has an important impact on quality of life. Topical corticosteroids (TCS) are the first-line therapy for this condition; however, they - Topical treatment for facial burns
Cochrane Systematic Reviews, 29-Jul-2020
Burn injuries are an important health problem. They occur frequently in the head and neck region. The face is the area central to a person's identity that provides our most expressive means of communication. Topical interventions are currently the corners - Topical treatment for vaginal candidiasis (thrush) in pregnancy
Cochrane Systematic Reviews, 23-Oct-2001
Vaginal candidiasis (moniliasis or thrush) is a common and frequently distressing infection for many women. It is even more common in pregnancy. There is no evidence that thrush in pregnancy is harmful to the baby. - Topical treatments for blepharokeratoconjunctivitis in children
Cochrane Systematic Reviews, 7-Feb-2017
Blepharokeratoconjunctivitis (BKC) is a type of inflammation of the surface of the eye and eyelids that involves changes of the eyelids, dysfunction of the meibomian glands, and inflammation of the conjunctiva and cornea. Chronic inflammation of the corne - Topical treatments for chronic plaque psoriasis
Cochrane Systematic Reviews, 28-Mar-2013
Chronic plaque psoriasis is the most common type of psoriasis, and it is characterised by redness, thickness, and scaling. First-line management of chronic plaque psoriasis is with topical treatments, including vitamin D analogues, topical corticosteroids - Topical treatments for cutaneous warts
Cochrane Systematic Reviews, 12-Sep-2012
Viral warts are a common skin condition, which can range in severity from a minor nuisance that resolve spontaneously to a troublesome, chronic condition. Many different topical treatments are available. - Topical treatments for fungal infections of the skin and nails of the foot.
Cochrane Systematic Reviews, 18-Jul-2007
Fungal infections of the feet normally occur in the outermost layer of the skin (epidermis). The skin between the toes is a frequent site of infection which can cause pain and itchiness. Fungal infections of the nail (onychomycosis) can affect the entire - Topical treatments for HIV-related oral ulcers
Cochrane Systematic Reviews, 5-Dec-2011
In HIV-infected adults, oral ulcers occur more frequently, last longer and produce more painful symptoms than in immunocompetent people. Oral aphthous ulcers observed during the course of HIV infection may be severe and can result in significant morbidity - Topical treatments for scalp psoriasis
Cochrane Systematic Reviews, 26-Feb-2016
People with chronic plaque psoriasis often have lesions on the scalp. Hair makes the scalp difficult to treat and the adjacent facial skin is particularly sensitive to topical treatments. - Topical umbilical cord care at birth
Cochrane Systematic Reviews, 4-Oct-2016
Umbilical cord infection caused many neonatal deaths before aseptic techniques were used. - Topical versus systemic antibiotics for chronic suppurative otitis media
Cochrane Systematic Reviews, 9-Feb-2021
Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear d - Topical Vitamin A, or its derivatives, for treating and preventing napkin dermatitis in infants
Cochrane Systematic Reviews, 19-Oct-2005
Napkin dermatitis (nappy or diaper rash) is a non-specific term used to describe inflammatory eruptions (rashes) in the napkin area. Most infants develop napkin dermatitis at least once during their infancy. Topical vitamin A has been suggested as a treat - Topically applied anaesthetics for treating perineal pain after childbirth
Cochrane Systematic Reviews, 29-Oct-2008
Perineal trauma is a major problem affecting millions of women around the world each year. The degree of perineal pain and discomfort associated with perineal trauma is often underestimated. Pain often interferes with basic daily activities for the woman - Topiramate add‐on therapy for drug‐resistant focal epilepsy
Cochrane Systematic Reviews, 23-Oct-2019
The majority of people with epilepsy have a good prognosis and their seizures are controlled by a single antiepileptic drug. However, up to 20% of patients from population-based studies, and up to 30% from clinical series (not population-based), develop d - Topiramate for acute affective episodes in bipolar disorder in adults
Cochrane Systematic Reviews, 3-Sep-2016
Bipolar disorder is a common recurrent illness with high levels of chronicity. Previous trials have suggested that the anticonvulsant topiramate may be efficacious in bipolar disorder. This is an update of a previous Cochrane review (last published 2006) - Topiramate for essential tremor
Cochrane Systematic Reviews, 14-Apr-2017
Essential tremor (ET) is one of the most common movement disorders. The management is primarily based on pharmacological agents and in clinical practice propranolol and primidone are considered the first-line therapy. However, these treatments can be inef - Topiramate for juvenile myoclonic epilepsy
Cochrane Systematic Reviews, 24-Nov-2021
Topiramate is a newer broad-spectrum antiepileptic drug (AED). Some studies have shown the benefits of topiramate in the treatment of juvenile myoclonic epilepsy (JME). However, there are no current systematic reviews to determine the efficacy and tolerab - Topiramate for neuropathic pain and fibromyalgia in adults
Cochrane Systematic Reviews, 30-Aug-2013
Topiramate is an antiepileptic drug with multiple possible mechanisms of action. Antiepileptic drugs are widely used to treat chronic neuropathic pain (pain due to nerve damage) and fibromyalgia, and many guidelines recommend them. - Topiramate for the prophylaxis of episodic migraine in adults
Cochrane Systematic Reviews, 24-Jun-2013
Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an update of a Cochrane
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