Showing 921-940 of 7110 for: Cochrane Systematic Reviews Back
- Bisphosphonates for the relief of pain secondary to bone metastases
Cochrane Systematic Reviews, 11-Aug-2009
Bisphosphonates form part of standard therapy for hypercalcemia and the prevention of skeletal events in some cancers. However, the role of bisphosphonates in pain relief for bony metastases remains uncertain.
- Bisphosphonates in multiple myeloma: a network meta-analysis
Cochrane Systematic Reviews, 20-Apr-2012
Bisphosphonates are specific inhibitors of osteoclastic activity and used in the treatment of patients with multiple myeloma (MM). While bisphosphonates are shown to be effective in reducing vertebral fractures and pain, their role in improving overall su
- Black cohosh (Cimicifuga spp.) for menopausal symptoms
Cochrane Systematic Reviews, 13-Sep-2012
Menopause can be a distressing and disruptive time for many women, with many experiencing hot flushes, night sweats, vaginal atrophy and dryness. Postmenopausal women are also at increased risk of osteoporosis. Interventions that decrease the severity and
- Bladder neck needle suspension for urinary incontinence in women
Cochrane Systematic Reviews, 16-Dec-2014
Bladder neck needle suspension is an operation traditionally used for moderate or severe stress urinary incontinence in women. About a third of adult women experience some urinary incontinence, and about a third of these have moderate or severe symptoms.
- Bladder training for urinary incontinence in adults
Cochrane Systematic Reviews, 4-Nov-2008
Urinary incontinence is a common and distressing problem. Bladder training aims to increase the interval between voids and is widely used for the treatment of urinary incontinence.
- Blood CEA levels for detecting recurrent colorectal cancer
Cochrane Systematic Reviews, 9-Dec-2015
Testing for carcino-embryonic antigen (CEA) in the blood is a recommended part of follow-up to detect recurrence of colorectal cancer following primary curative treatment. There is substantial clinical variation in the cut-off level applied to trigger fur
- Blood pressure control for diabetic retinopathy
Cochrane Systematic Reviews, 28-Jan-2015
Diabetic retinopathy is a common complication of diabetes and a leading cause of visual impairment and blindness. Research has established the importance of blood glucose control to prevent development and progression of the ocular complications of diabet
- Blood pressure lowering efficacy of alpha blockers for primary hypertension
Cochrane Systematic Reviews, 10-Jul-2012
Alpha blockers are occasionally prescribed for hypertension so it is important to determine and compare their effects on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE).
- Blood pressure lowering efficacy of angiotensin converting enzyme (ACE) inhibitors for primary hypertension
Cochrane Systematic Reviews, 11-Aug-2009
ACE inhibitors are widely prescribed for hypertension so it is essential to determine and compare their effects on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE).
- Blood pressure lowering efficacy of angiotensin receptor blockers for primary hypertension
Cochrane Systematic Reviews, 11-Aug-2009
Angiotensin receptor blockers (ARBs) are widely prescribed for hypertension so it is essential to determine and compare their effects on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE).
- Blood pressure lowering efficacy of beta-1 selective beta blockers for primary hypertension
Cochrane Systematic Reviews, 9-Mar-2016
Beta blockers are commonly used to treat hypertension. The blood pressure reading is the primary tool for physicians and patients to assess the efficacy of the treatment. The blood pressure lowering effect of beta-1 selective blockers is not known.
- Blood pressure lowering efficacy of beta-blockers as second-line therapy for primary hypertension
Cochrane Systematic Reviews, 11-Nov-2009
Beta-blockers are one of the more commonly prescribed classes of anti-hypertensive drugs, both as first-line and second-line.
- Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Cochrane Systematic Reviews, 3-Mar-2016
Blood pressure is a commonly measured risk factor for non-fatal and fatal cardiovascular adverse events such as heart attacks and strokes. Clinical trials have suggested that coenzyme Q10, a non-prescription nutritional supplement, can effectively lower b
- Blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertension
Cochrane Systematic Reviews, 12-Aug-2009
Diuretics are widely prescribed for hypertension not only as a first-line drug but also as a second-line drug. Therefore, it is essential to determine the effects of diuretics on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE
- Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension
Cochrane Systematic Reviews, 22-Aug-2015
Drugs with combined alpha and beta blocking activity are commonly prescribed to treat hypertension. However, the blood pressure (BP) lowering efficacy of this class of beta blockers has not been systematically reviewed and quantified.
- Blood pressure lowering efficacy of nonselective beta-blockers for primary hypertension
Cochrane Systematic Reviews, 28-Feb-2014
Beta-blockers are one of the classes of drugs frequently used to treat hypertension. Quantifying the blood pressure (BP) lowering effects of nonselective beta-blockers provides important information that aids clinical decision making.
- Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension
Cochrane Systematic Reviews, 26-Nov-2014
Partial agonists are a subclass of beta blockers used to treat hypertension in many countries. Partial agonist act by stimulating beta receptors when they are quiescent and blocking beta receptors when they are active. The blood pressure (BP) lowering eff
- Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension
Cochrane Systematic Reviews, 18-Oct-2012
Potassium-sparing diuretics, which block the epithelial sodium channel (ENaC), are widely prescribed for hypertension as a second-line drug in patients taking other diuretics (e.g. thiazide diuretics) and much less commonly prescribed as monotherapy. Ther
- Blood pressure lowering efficacy of renin inhibitors for primary hypertension
Cochrane Systematic Reviews, 10-Aug-2011
Hypertension is a chronic condition associated with an increased risk of mortality and morbidity. The renin-angiotensin-aldosterone system is an important target site for five antihypertensive drug classes: beta blockers, renin inhibitors, ACE inhibitors,
- Blood pressure lowering efficacy of reserpine for primary hypertension
Cochrane Systematic Reviews, 12-Aug-2009
Many antihypertensive agents exist today for the treatment of primary hypertension (systolic blood pressure =140 mmHg and/or diastolic blood pressure =90 mmHg). Randomised controlled trials have been carried out to investigate the evidence for these agent
