Showing 81-100 of 157 for: Cochrane Systematic Reviews > Eye and ear 
- Intratympanic gentamicin for Ménière's disease or syndrome
Cochrane Systematic Reviews, 6-Mar-2011
Ménière's disease is characterised by three major symptoms: vertigo, deafness and tinnitus, which may be accompanied by aural fullness, all of which are discontinuous and variable in intensity. While discontinuous, these symptoms are synchronous. Intratym
- Intratympanic steroids for Ménière's disease or syndrome
Cochrane Systematic Reviews, 13-Jun-2011
Ménière's disease is a disorder characterised by hearing loss, tinnitus and disabling vertigo. The use of intratympanic steroids to reduce the severity of these symptoms has been gaining popularity.
- Intravitreal low molecular weight heparin and 5-Fluorouracil for the prevention of proliferative vitreoretinopathy following retinal reattachment surgery
Cochrane Systematic Reviews, 11-Nov-2012
Proliferative vitreoretinopathy (PVR) is a significant cause of failure in retinal reattachment surgery. Various pharmacological agents have shown potential benefit in reducing postoperative PVR risk.
- Intravitreal steroids for macular edema in diabetes
Cochrane Systematic Reviews, 19-Oct-2008
Macular edema is secondary to leakage from diseased retinal capillaries and is an important cause of poor central visual acuity in patients with diabetic retinopathy.
- Ivermectin for onchocercal eye disease (river blindness)
Cochrane Systematic Reviews, 20-Jul-2012
It is believed that ivermectin (a microfilaricide) could prevent blindness due to onchocerciasis. However, when given to everyone in communities where onchocerciasis is common, the effects of ivermectin on lesions affecting the eye are uncertain and data
- Laser photocoagulation for choroidal neovascularisation in pathologic myopia
Cochrane Systematic Reviews, 20-Oct-2008
Pathologic myopia is usually defined as the need for a spectacle correction of -6 diopters or higher. Choroidal neovascularisation (CNV) is the most commonly occurring cause of visual loss in people with pathologic myopia. In myopic macular degeneration t
- Laser photocoagulation for neovascular age-related macular degeneration
Cochrane Systematic Reviews, 15-Oct-2008
Laser photocoagulation was the first treatment introduced to try to halt the progression of neovascular age-related macular degeneration (AMD), in which newly formed vessels or choroidal neovascularisation (CNV) grow under the macula leading to the occurr
- Laser trabeculoplasty for open‐angle glaucoma and ocular hypertension
Cochrane Systematic Reviews, 9-Aug-2022
Open-angle glaucoma (OAG) is an important cause of blindness worldwide. Laser trabeculoplasty, a treatment modality, still does not have a clear position in the treatment sequence.
- Laser treatment of drusen to prevent progression to advanced age-related macular degeneration
Cochrane Systematic Reviews, 21-Oct-2015
Drusen are amorphous yellowish deposits beneath the sensory retina. People with drusen, particularly large drusen, are at higher risk of developing age-related macular degeneration (AMD). The most common complication in AMD is choroidal neovascularisation
- Laser-assisted in-situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia
Cochrane Systematic Reviews, 13-Dec-2012
Myopia (also known as short-sightedness or near-sightedness) is an ocular condition in which the refractive power of the eye is greater than is required, resulting in light from distant objects being focused in front of the retina instead of directly on i
- Late (≥ 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants
Cochrane Systematic Reviews, 11-Nov-2021
Many infants born preterm develop bronchopulmonary dysplasia (BPD), with lung inflammation playing a role. Corticosteroids have powerful anti-inflammatory effects and have been used to treat individuals with established BPD. However, it is unclear whether
- Lens extraction for chronic angle-closure glaucoma
Cochrane Systematic Reviews, 17-Oct-2008
Angle-closure glaucoma is characterized by obstruction to the outflow of aqueous humor and consequent rise in intraocular pressure. The obstruction may result from an anatomical predisposition of the eye or may be due to pathophysiologic processes in any
- Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity
Cochrane Systematic Reviews, 7-Dec-2011
Screening examinations for retinopathy of prematurity (ROP) are performed routinely in the neonatal intensive care unit and are a recognised cause of pain in the newborn.
- Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract
Cochrane Systematic Reviews, 18-Nov-2014
Age-related cataract is the opacification of the lens, which occurs as a result of denaturation of lens proteins. Age-related cataract remains the leading cause of blindness globally, except in the most developed countries. A key question is what is the b
- Medical interventions for fungal keratitis
Cochrane Systematic Reviews, 8-Apr-2015
Fungal keratitis is a fungal infection of the cornea. It is common in lower income countries, particularly in agricultural areas but relatively uncommon in higher income countries. Although there are medications available, their effectiveness is unclear.
- Medical interventions for primary open angle glaucoma and ocular hypertension
Cochrane Systematic Reviews, 31-Oct-2008
Primary open angle glaucoma (POAG) is a progressive optic neuropathy with an elevated intraocular pressure (IOP), where the optic nerve head becomes pathologically excavated and the visual field (VF) is characteristically altered. Ocular hypertension (OHT
- Medical interventions for the prevention of platinum-induced hearing loss in children with cancer
Cochrane Systematic Reviews, 1-Jul-2014
Platinum-based therapy, including cisplatin, carboplatin and/or oxaliplatin, is used to treat a variety of paediatric malignancies. Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to
- Medical interventions for traumatic hyphema
Cochrane Systematic Reviews, 30-Nov-2013
Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye. Hyphema uncommonly causes permanent loss of vision. Associated trauma (e.g. corneal staining,
- Medical versus surgical interventions for open angle glaucoma
Cochrane Systematic Reviews, 8-Aug-2012
Open angle glaucoma (OAG) is a common cause of blindness.
- Modifications of the Epley (canalith repositioning) manoeuvre for posterior canal benign paroxysmal positional vertigo (BPPV)
Cochrane Systematic Reviews, 12-Mar-2012
Benign paroxsymal positional vertigo (BPPV) is a syndrome characterised by short-lived episodes of vertigo associated with rapid changes in head position. It is a common cause of vertigo presenting to primary care and specialist otolaryngology (ENT) clini
