- Bifeprunox versus placebo for schizophrenia
Cochrane Systematic Reviews, 12-Oct-2016
Bifeprunox is a novel antipsychotic drug designed to treat schizophrenia. However, research into the drug was ceased in 2009 due to rejection of licence to go to market by the US Food and Drug Administration (FDA), who could not approve the drug for acute - Bilateral versus unilateral hearing aids for bilateral hearing impairment in adults
Cochrane Systematic Reviews, 18-Dec-2017
Acquired hearing loss is common and its incidence increases markedly with age. In most people, 'age-related' hearing loss is sensorineural (due to the loss of cochlear hair cells) and bilateral, affecting both ears to the same degree. Hearing loss categor - Bile acids for liver‐transplanted patients
Cochrane Systematic Reviews, 17-Mar-2010
Liver transplantation has become a widely accepted form of treatment for numerous end-stage liver diseases. Bile acids may decrease allograft rejection after liver transplantation by changing the expression of major histocompatibility complex class molecu - Bile acids for non‐alcoholic fatty liver disease and/or steatohepatitis
Cochrane Systematic Reviews, 9-Jul-2020
- Bile acids for primary sclerosing cholangitis
Cochrane Systematic Reviews, 19-Jan-2011
Primary sclerosing cholangitis is a progressive chronic cholestatic liver disease that usually leads to the development of cirrhosis. Studies evaluating bile acids in the treatment of primary sclerosing cholangitis have shown a potential benefit of their - Bile acids for viral hepatitis
Cochrane Systematic Reviews, 17-Oct-2007
Trials have assessed bile acids for patients with viral hepatitis, but no consensus has been reached regarding their usefulness. - Binocular versus standard occlusion or blurring treatment for unilateral amblyopia in children aged three to eight years
Cochrane Systematic Reviews, 7-Feb-2022
Current treatments for amblyopia, typically patching or pharmacological blurring, have limited success. Less than two-thirds of children achieve good acuity of 0.20 logMAR in the amblyopic eye, with limited improvement of stereopsis, and poor adherence to - Bioabsorbable versus metallic interference screws for graft fixation in anterior cruciate ligament reconstruction
Cochrane Systematic Reviews, 22-Jul-2016
Anterior cruciate ligament (ACL) tears are frequently treated with surgical reconstruction with grafts, frequently patella tendon or hamstrings. Interference screws are often used to secure the graft in bone tunnels in the femur and tibia. This review exa - Biochemical tests of placental function for assessment in pregnancy
Cochrane Systematic Reviews, 15-Aug-2012
Biochemical tests of placental or feto-placental function were widely used in the 1960s and 1970s in high-risk pregnancies to try to predict, and thus try to avoid, adverse fetal outcome. - Biochemical tests of placental function versus ultrasound assessment of fetal size for stillbirth and small-for-gestational-age infants
Cochrane Systematic Reviews, 7-Jun-2019
Stillbirth affects 2.6 million pregnancies worldwide each year. Whilst the majority of cases occur in low- and middle-income countries, stillbirth remains an important clinical issue for high-income countries (HICs) - with both the UK and the USA reportin - Biocompatible dialysis fluids for peritoneal dialysis
Cochrane Systematic Reviews, 26-Oct-2018
Biocompatible peritoneal dialysis (PD) solutions, including neutral pH, low glucose degradation product (GDP) solutions and icodextrin, have previously been shown to favourably influence some patient-level outcomes, albeit based on generally sub-optimal q - Biocompatible hemodialysis membranes for acute renal failure
Cochrane Systematic Reviews, 23-Jan-2008
Acute renal failure (ARF) is associated with substantial morbidity and mortality. Some studies have reported a survival advantage among patients dialyzed with biocompatible membranes (BCM) compared to bioincompatible membranes (BICM). These findings were - Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb
Cochrane Systematic Reviews, 7-Dec-2022
Traumatic peripheral nerve injury is common and incurs significant cost to individuals and society. Healing following direct nerve repair or repair with autograft is slow and can be incomplete. Several bioengineered nerve wraps or devices have become avai - Biofeedback and/or sphincter exercises for the treatment of faecal incontinence in adults
Cochrane Systematic Reviews, 13-Jun-2012
Faecal incontinence is a particularly embarrassing and distressing condition with significant medical, social and economic implications. Anal sphincter exercises (pelvic floor muscle training) and biofeedback therapy have been used to treat the symptoms o - Biofeedback for pain management during labour
Cochrane Systematic Reviews, 8-May-2011
Labour is often associated with pain and discomfort caused by a complex and subjective interaction of multiple factors, and should be understood within a multi-dimensional and multi-disciplinary framework. Within the non-pharmacological approach, biofeedb - Biofeedback for treatment of chronic idiopathic constipation in adults
Cochrane Systematic Reviews, 21-Nov-2014
Biofeedback therapy has been used to treat the symptoms of people with chronic constipation referred to specialist services within secondary and tertiary care settings. However, different methods of biofeedback are used within different centres and the ma - Biofeedback for treatment of irritable bowel syndrome
Cochrane Systematic Reviews, 12-Nov-2019
Irritable bowel syndrome (IBS) is a prevalent condition that currently lacks highly effective therapies for its management. Biofeedback has been proposed as a therapy that may help individuals learn to exert conscious control over sympatho-vagal balance a - Bioidentical hormones for women with vasomotor symptoms
Cochrane Systematic Reviews, 28-Jul-2016
Various hormone therapies (HT) are available to treat menopausal vasomotor symptoms. Bioidentical hormones are chemically identical to those produced by the human body, and several types are well-tested and available on prescription. Many women have opted - Biologic interventions for fatigue in rheumatoid arthritis
Cochrane Systematic Reviews, 6-Jun-2016
Fatigue is a common and potentially distressing symptom for patients with rheumatoid arthritis (RA), with no accepted evidence-based management guidelines. Evidence suggests that biologic interventions improve symptoms and signs in RA as well as reducing - Biologic or tofacitinib monotherapy for rheumatoid arthritis in people with traditional disease‐modifying anti‐rheumatic drug (DMARD) failure: a Cochrane Systematic Review and network meta‐analysis (NMA)
Cochrane Systematic Reviews, 17-Nov-2016
We performed a systematic review, a standard meta-analysis and network meta-analysis (NMA), which updates the 2009 Cochrane Overview, 'Biologics for rheumatoid arthritis (RA)'. This review is focused on biologic monotherapy in people with RA in whom treat
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