Showing 121-140 of 166 for: Cochrane Systematic Reviews > Dermatologic 
- Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis
Cochrane Systematic Reviews, 30-Sep-2020
Staphylococcus aureus causes pulmonary infection in young children with cystic fibrosis. Prophylactic antibiotics are prescribed hoping to prevent such infection and lung damage. Antibiotics have adverse effects and long-term use might lead to infection w
- Prophylactic oral/topical non‐absorbed antifungal agents to prevent invasive fungal infection in very low birth weight infants
Cochrane Systematic Reviews, 24-Oct-2015
Invasive fungal infection is an important cause of mortality and morbidity in very preterm or very low birth weight infants. Uncertainty exists about the effect of prophylactic oral/topical non-absorbed antifungals to reduce mucocutaneous colonisation and
- Psychological and educational interventions for atopic eczema in children
Cochrane Systematic Reviews, 7-Jan-2014
Psychological and educational interventions have been used as an adjunct to conventional therapy for children with atopic eczema to enhance the effectiveness of topical therapy. This is an update of the original Cochrane review.
- Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer
Cochrane Systematic Reviews, 12-Dec-2014
This is an update of a Cochrane review first published in The Cochrane Library in Issue 2, 2002 and previously updated in 2004, 2007 and 2010.
- Repositioning for treating pressure ulcers
Cochrane Systematic Reviews, 5-Jan-2015
Pressure, from lying or sitting on a particular part of the body results in reduced oxygen and nutrient supply, impaired drainage of waste products and damage to cells. If a patient with an existing pressure ulcer continues to lie or bear weight on the af
- Saline irrigation for the management of skin extravasation injury in neonates
Cochrane Systematic Reviews, 19-Jul-2017
Extravasation injury, a complication commonly seen in the neonatal intensive care unit, can result in scarring with cosmetic and functional sequelae. A wide variety of treatments are available, including subcutaneous irrigation with saline (with or withou
- Silicone gel sheeting for preventing and treating hypertrophic and keloid scars
Cochrane Systematic Reviews, 12-Sep-2013
Keloid and hypertrophic scars are common and are caused by a proliferation of dermal tissue following skin injury. They cause functional and psychological problems for patients, and their management can be difficult. The use of silicone gel sheeting to pr
- Silver based wound dressings and topical agents for treating diabetic foot ulcers
Cochrane Systematic Reviews, 17-Jan-2011
Foot ulceration affects 15 to 20% of people with diabetes. It is a major precursor to amputation in this patient group, and early and appropriate treatment provides the greatest opportunity for healing. The use of silver for its antimicrobial properties h
- Skin grafting for venous leg ulcers
Cochrane Systematic Reviews, 31-Jan-2013
Venous leg ulceration is a recurrent, chronic, disabling condition. It affects up to one in 100 people at some time in their lives. Standard treatments are simple dressings and compression bandages or stockings. Sometimes, despite treatment, ulcers remain
- Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne
Cochrane Systematic Reviews, 15-Mar-2011
Hirsutism is the presence of excessive hair growth in women and is an important cosmetic condition often resulting in severe distress. The most common cause is by increased production of male sex hormones (androgens). It is also affected by increased sens
- Staples versus sutures for closing leg wounds after vein graft harvesting for coronary artery bypass surgery.
Cochrane Systematic Reviews, 24-Nov-2011
Surgical site infection (SSI) after saphenous vein graft harvesting is a complication occurring in up to 18% of patients who undergo coronary artery bypass surgery (CABG). It is not known whether the method of skin closure influences the infection rate.
- Statins and fibrates for preventing melanoma
Cochrane Systematic Reviews, 19-Oct-2005
Effective treatment for advanced melanoma is lacking. While no drug therapy currently exists for prevention of melanoma, in vitro, case-control, and animal model evidence suggest that lipid-lowering medications, commonly taken for high cholesterol, might
- Support surfaces for pressure ulcer prevention
Cochrane Systematic Reviews, 3-Sep-2015
Pressure ulcers (i.e. bedsores, pressure sores, pressure injuries, decubitus ulcers) are areas of localised damage to the skin and underlying tissue. They are common in the elderly and immobile, and costly in financial and human terms. Pressure-relieving
- Support surfaces for treating pressure ulcers
Cochrane Systematic Reviews, 11-Oct-2018
Pressure ulcers are treated by reducing pressure on the areas of damaged skin. Special support surfaces (including beds, mattresses and cushions) designed to redistribute pressure, are widely used as treatments. The relative effects of different support s
- Surgery for cervical intraepithelial neoplasia
Cochrane Systematic Reviews, 2-Dec-2013
Cervical intraepithelial neoplasia (CIN) is the most common pre-malignant lesion. Atypical squamous changes occur in the transformation zone of the cervix with mild, moderate or severe changes described by their depth (CIN 1, 2 or 3). Cervical intraepithe
- Surgery for deep venous insufficiency
Cochrane Systematic Reviews, 30-Sep-2021
Chronic deep venous insufficiency is caused by incompetent vein valves, blockage of large-calibre leg veins, or both; and causes a range of symptoms including recurrent ulcers, pain and swelling. Most surgeons accept that well-fitted graduated compression
- Surgery for obstructive sleep apnoea in adults
Cochrane Systematic Reviews, 19-Oct-2005
Obstructive sleep apnoea/hypopnoea syndrome(OSAHS) is the periodic reduction or cessation of airflow during sleep. The syndrome is associated with loud snoring, disrupted sleep and observed apnoeas. Surgery for obstructive sleep apnoea/hypopnoea syndrome
- Surgery for varicose veins: use of tourniquet
Cochrane Systematic Reviews, 10-Jun-2013
Varicose vein surgery is a common surgical procedure but there is no consensus regarding the best surgical technique. The use of tourniquets during varicose vein surgery has been advocated as a means of reducing the potential for blood loss during the ope
- Surgery versus sclerotherapy for the treatment of varicose veins
Cochrane Systematic Reviews, 18-Oct-2004
Varicose veins are a relatively common condition and account for around 54,000 in-patient hospital episodes per year. The two most common interventions for varicose veins are surgery and sclerotherapy. However, there is little comparative data regarding t
- Surgical excision margins for primary cutaneous melanoma
Cochrane Systematic Reviews, 7-Oct-2009
Cutaneous melanoma accounts for 75% of skin cancer deaths. Standard treatment is surgical excision with a safety margin some distance from the borders of the primary tumour. The purpose of the safety margin is to remove both the complete primary tumour an
