- Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease
Cochrane Systematic Reviews, 14-Mar-2012
Previous Cochrane reviews have considered the use of cholinesterase inhibitors in both Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB). The clinical features of DLB and PDD have much in common and are distinguished primarily on - Cholinesterase inhibitors for mild cognitive impairment
Cochrane Systematic Reviews, 5-Jul-2016
Mild cognitive impairment is hypothesised to represent a pre-clinical stage of dementia but forms a heterogeneous group with variable prognosis. - Cholinesterase inhibitors for Parkinson's disease dementia
Cochrane Systematic Reviews, 5-May-2008
The loss of cholinergic, dopaminergic and noradrenergic innervations seen in Parkinson's Disease Dementia (PDD) suggest a potential role for cholinesterase inhibitors. Concerns have been expressed about a theoretical worsening of Parkinson's disease relat - Cholinesterase inhibitors for rarer dementias associated with neurological conditions
Cochrane Systematic Reviews, 17-Feb-2015
Rarer dementias include Huntington's disease (HD), cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), frontotemporal dementia (FTD), dementia in multiple sclerosis (MS) and progressive supranuclear palsy - Cholinesterase inhibitors for the treatment of delirium in non‐ICU settings
Cochrane Systematic Reviews, 28-Jun-2018
Delirium is a common clinical syndrome defined as alterations in attention with an additional disturbance in cognition or perception, which develop over a short period of time and tend to fluctuate during the course of the episode. Delirium is commonly tr - Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta‐analysis
Cochrane Systematic Reviews, 22-Feb-2021
Vascular cognitive impairment (VCI) describes a broad spectrum of cognitive impairments caused by cerebrovascular disease, ranging from mild cognitive impairment to dementia. There are currently no pharmacological treatments recommended for improving eith - Chondroitin for osteoarthritis
Cochrane Systematic Reviews, 28-Jan-2015
Osteoarthritis, a common joint disorder, is one of the leading causes of disability. Chondroitin has emerged as a new treatment. Previous meta-analyses have shown contradictory results on the efficacy of chondroitin. This, in addition to the publication o - Chorion villus sampling versus amniocentesis for prenatal diagnosis
Cochrane Systematic Reviews, 28-Oct-2008
Amniocentesis test results are usually available only after 18 weeks gestation. Chorion villus sampling (CVS) may be performed transabdominally or transvaginally, usually between 10 and 12 weeks gestation. - Chromium picolinate supplementation for overweight or obese adults
Cochrane Systematic Reviews, 29-Nov-2013
Obesity is a global public health threat. Chromium picolinate (CrP) is advocated in the medical literature for the reduction of body weight, and preparations are sold as slimming aids in the USA and Europe, and on the Internet. - Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum
Cochrane Systematic Reviews, 7-Apr-2016
Although conventional colonoscopy is the most accurate test available for the investigation of the colorectum for polyps, data exist that raise concerns about its sensitivity. Chromoscopy (spraying dye onto the surface of the colon to make polyps more vis - Chronic disease management programmes for adults with asthma
Cochrane Systematic Reviews, 26-May-2015
The burden of asthma on patients and healthcare systems is substantial. Interventions have been developed to overcome difficulties in asthma management. These include chronic disease management programmes, which are more than simple patient education, enc - Chronic non‐invasive ventilation for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 9-Aug-2021
Chronic non-invasive ventilation (NIV) is increasingly being used to treat people with COPD who have respiratory failure, but the evidence supporting this treatment has been conflicting. - Chronotherapy versus conventional statins therapy for the treatment of hyperlipidaemia
Cochrane Systematic Reviews, 26-Nov-2016
Elevated levels of total cholesterol and low-density lipoprotein play an important role in the development of atheromas and, therefore, in cardiovascular diseases. Cholesterol biosynthesis follows a circadian rhythm and is principally produced at night (b - Chuanxiong preparations for preventing stroke
Cochrane Systematic Reviews, 3-Jun-2016
Stroke is a major healthcare problem and is one of the leading causes of death and serious long-term disability. Prevention of stroke is considered an important strategy. Chuanxiong is traditionally used in China in the treatment and prevention of stroke. - Chuanxiong-type preparations for acute ischemic stroke
Cochrane Systematic Reviews, 23-Jul-2008
Stroke, 88% of which are ischemic, is a common cause of death and disability all over the world. Chuanxiong has been reported to be beneficial in treating stroke. However, the strength of evidence to support its use is unclear. - Ciclesonide versus other inhaled corticosteroids for chronic asthma in children
Cochrane Systematic Reviews, 21-Dec-2012
Inhaled corticosteroids (ICS) are the cornerstone of asthma maintenance treatment in children. Particularly among parents, there is concern about the safety of ICS as studies in children have shown reduced growth. Small-particle-size ICS targeting the sma - Ciclesonide versus other inhaled steroids for chronic asthma in children and adults
Cochrane Systematic Reviews, 23-Apr-2008
Inhaled corticosteroids (ICS) are an integral part of asthma management, and act as an anti-inflammatory agent in the airways of the lung. These agents confer both significant benefit in terms of symptom management and improvement in lung function, but ma - Ciclesonide versus placebo for chronic asthma in adults and children
Cochrane Systematic Reviews, 23-Apr-2008
Inhaled corticosteroids are an integral part of asthma management, and act as an anti-inflammatory agent in the airways of the lung. These agents confer significant benefit in terms of symptom management and improvement in lung function, but may also caus - Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease
Cochrane Systematic Reviews, 19-Jul-2004
Amyotrophic lateral sclerosis, also known as motor neuron disease, is a fatal neuromuscular disease characterized by progressive muscle weakness resulting in paralysis. It might be treated with ciliary neurotrophic factor. This is an updated review. An up - Cilostazol for intermittent claudication
Cochrane Systematic Reviews, 30-Jun-2021
Peripheral arterial disease (PAD) affects between 4% and 12% of people aged 55 to 70 years, and 20% of people over 70 years. A common complaint is intermittent claudication (exercise-induced lower limb pain relieved by rest). These patients have a three-
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