Showing 141-160 of 371 for: Cochrane Systematic Reviews > Oncology 
- High-dose chemotherapy for children and young adults with stage IV rhabdomyosarcoma
Cochrane Systematic Reviews, 8-Nov-2010
Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Prognosis for patients with metastatic disease has not improved significantly in the past decades. High-dose chemotherapy (HDC) seems to be an attractive option to treat minimal residua
- High-dose chemotherapy with autologous stem cell transplantation in the first line treatment of aggressive Non-Hodgkin Lymphoma (NHL) in adults
Cochrane Systematic Reviews, 2-Apr-2011
High-dose chemotherapy with autologous stem cell support (HDT) has been proven effective in relapsed aggressive non-Hodgkin lymphoma (NHL). However, conflicting results of HDT as part of first-line treatment have been reported in randomised controlled tri
- High-dose therapy with autologous stem cell transplantation versus chemotherapy or immuno-chemotherapy for follicular lymphoma in adults
Cochrane Systematic Reviews, 15-Nov-2011
Follicular lymphoma (FL) is the most common indolent and second most common Non-Hodgkin`s lymphoma (NHL) in the Western world. Standard treatment usually includes rituximab and chemotherapy. High-dose therapy (HDT) followed by autologous stem cell transpl
- Histamine type 2 receptor antagonists as adjuvant treatment for resected colorectal cancer
Cochrane Systematic Reviews, 3-Jul-2012
Anecdotal reports of tumour regression with histamine type 2 receptor antagonists (H2RAs) have lead to a series of trials with this class of drug as adjuvant therapy to try and improve outcomes in patients with resected colorectal cancers. There was a pla
- Homeopathic medicines for adverse effects of cancer treatments
Cochrane Systematic Reviews, 15-Apr-2009
Homeopathic medicines are used by patients with cancer, often alongside conventional treatment. Cancer treatments can cause considerable morbidity and one of the reasons patients use homeopathic medicines is to help with adverse effects.
- Hormonal therapy in advanced or recurrent endometrial cancer
Cochrane Systematic Reviews, 1-Apr-2015
Endometrial cancer is a cancer of the lining of the womb and worldwide is the seventh most common cancer in women. Treatment with hormones is thought to be beneficial in patients with endometrial cancer.
- Hormone therapy in postmenopausal women and risk of endometrial hyperplasia
Cochrane Systematic Reviews, 15-Aug-2012
Reduced circulating estrogen levels around the time of the menopause can induce unacceptable symptoms that affect the health and well-being of women. Hormone therapy (both unopposed estrogen and estrogen/progestogen combinations) is an effective treatment
- Hyperbaric oxygen therapy for late radiation tissue injury
Cochrane Systematic Reviews, 28-Apr-2016
Cancer is a significant global health problem. Radiotherapy is a treatment for many cancers and about 50% of people having radiotherapy will be long-term survivors. Some will experience late radiation tissue injury (LRTI) developing months or years later.
- Hyperbaric oxygenation for tumour sensitisation to radiotherapy
Cochrane Systematic Reviews, 11-Apr-2018
Cancer is a common disease and radiotherapy is one well-established treatment for some solid tumours. Hyperbaric oxygenation therapy (HBOT) may improve the ability of radiotherapy to kill hypoxic cancer cells, so the administration of radiotherapy while b
- Hyperfractionated or accelerated radiotherapy for head and neck cancer
Cochrane Systematic Reviews, 8-Dec-2010
Several trials have studied the role of altered fractionation radiotherapy in head and neck squamous cell carcinoma, but the effect of such treatment on survival is not clear.
- Hypothalamic‐pituitary‐adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia
Cochrane Systematic Reviews, 6-Nov-2017
Glucocorticoids play a major role in the treatment of acute lymphoblastic leukaemia (ALL). However, supraphysiological doses can suppress the hypothalamic-pituitary-adrenal (HPA) axis. HPA axis suppression resulting in reduced cortisol response may cause
- Immediate versus delayed reconstruction following surgery for breast cancer
Cochrane Systematic Reviews, 17-Jul-2011
Breast cancer is the most prevalent cancer in women and has a lifetime incidence of one in nine in the UK. Curative treatment requires surgery, and may involve adjuvant and neo-adjuvant therapy. In many women, post-mastectomy breast reconstruction is esse
- Immunosuppressive agents for myasthenia gravis
Cochrane Systematic Reviews, 2-Nov-2008
The benefits of different immunosuppressants for myasthenia gravis (MG) are unclear.
- Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome
Cochrane Systematic Reviews, 15-Nov-2021
Primary membranous nephropathy (PMN) is a common cause of nephrotic syndrome in adults. Without treatment, approximately 30% of patients will experience spontaneous remission and one third will have persistent proteinuria. Approximately one-third of patie
- Immunotherapy for advanced renal cell cancer
Cochrane Systematic Reviews, 29-Dec-2015
The course of advanced renal cell carcinoma is extremely variable, ranging from spontaneous remission to disease progression refractory to chemotherapy. Immunotherapy has held promise of improved outcomes based on uncontrolled studies and randomized contr
- Influenza vaccination in children being treated with chemotherapy for cancer
Cochrane Systematic Reviews, 1-Aug-2013
Influenza infection is a potential cause of severe morbidity in children with cancer; therefore vaccination against influenza is recommended. However, data are conflicting regarding the immune response to influenza vaccination in children with cancer, and
- Information interventions for orienting patients and their carers to cancer care facilities
Cochrane Systematic Reviews, 16-Nov-2011
Cancer patients experience distress and anxiety related to their diagnosis, treatment and the unfamiliar cancer centre. Strategies with the aim of orienting patients to a cancer care facility may improve patient outcomes. Although meeting patients' inform
- Interferon‐alpha for maintenance of follicular lymphoma
Cochrane Systematic Reviews, 20-Jan-2010
Indolent non-Hodgkin's lymphoma, in particular follicular lymphoma (FL), is characterized by multiple remissions and relapses. Several studies have used interferon-alpha (IFN) to control this disease, both as induction and as maintenance therapy. It is no
- Intermittent versus continuous androgen suppression for prostatic cancer
Cochrane Systematic Reviews, 17-Jan-2012
After lung cancer, prostate cancer is the most common cause of death among males. The aim of treatment is to prevent disease-related morbidity and mortality while minimizing intervention-related adverse events. Androgen suppression therapy (AST) to reduce
- Interventions for actinic keratoses
Cochrane Systematic Reviews, 12-Dec-2012
Actinic keratoses are a skin disease caused by long-term sun exposure, and their lesions have the potential to develop into squamous cell carcinoma. Treatments for actinic keratoses are sought for cosmetic reasons, for the relief of associated symptoms, o
