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Exciting News: Introducing the New Essential Evidence Plus!

We are thrilled to announce that a brand-new version of Essential Evidence Plus is on its way! Mark your calendars for the launch date, September 11th, as we are introducing a modern, mobile-first application that will revolutionize your experience. With this update, accessing our valuable content will be easier and more convenient than ever before.

What to Expect from the New Essential Evidence Plus:

  1. Modern Mobile-First Experience: Our new application has been meticulously designed with a mobile-first approach. No matter what device you're using, whether it's a smartphone, tablet, or desktop, you'll enjoy a seamless and intuitive user experience.
  2. Enhanced Accessibility: We understand the importance of accessing content from anywhere, at any time. The new Essential Evidence Plus will provide you with the flexibility to explore our extensive collection of evidence-based resources on the go, making it easier to stay up to date with the latest medical knowledge and interactive tools.
  3. Improved User Interface: We have revamped our user interface to ensure effortless navigation and a visually appealing experience. Finding the information, you need will be quicker and more intuitive, saving you valuable time and effort.

Essential Evidence Plus will be available to users during this transition. However, please note that ability to create new trial and individual subscriptions will not be available from September 8th to September 11th 7:00 AM EST. During this period, we will be working diligently to transfer our existing system to the upgraded platform, ensuring a seamless transition for all users.

We apologize for any inconvenience caused by this temporary interruption. Rest assured, our team is committed to bringing you a superior user experience, and we appreciate your patience and understanding during this time.

Stay Tuned for the New Essential Evidence Plus!

We are counting down the days until September 11th when the new Essential Evidence Plus will be available for you to explore. Get ready to unlock a wealth of evidence-based resources that empower you in your medical decision-making process.

Thank you for your continued support, and we look forward to delivering an exceptional experience with the all-new Essential Evidence Plus!

Essential Evidence Plus

Searching & Browsing: Databases Searched

Essential Evidence Plus searches 7 different databases. Select one of the databases listed below for a description of the database and its purpose, as well as an example of how it can be used in the clinical decision process.

These additional resources are also available:


Understanding the diagnostic calculators

The following are descriptions of the terms used in the Diagnostic and H&P test calculators.

Pretest: Best estimate of percent with disease before any testing

Sensitivity: Percent with disease who have a positive test

Specificity: Percent without disease who have a negative test

LR: Likelihood ratio for each level of test. The higher it is, the better it rules in disease. The lower it is, the better it rules it out.

LR+: Positive likelihood ratio (how well a positive test rules-in disease)

LR-: Negative likelihood ratio (how well a negative test rules-out disease)

LR = 1: No change in disease likelihood

Prob: Probability of disease for patients with this test result