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Exciting News: Introducing the New Essential Evidence Plus!

We are thrilled to announce that a brand-new version of Essential Evidence Plus is on its way! Mark your calendars for the launch date, September 11th, as we are introducing a modern, mobile-first application that will revolutionize your experience. With this update, accessing our valuable content will be easier and more convenient than ever before.

What to Expect from the New Essential Evidence Plus:

  1. Modern Mobile-First Experience: Our new application has been meticulously designed with a mobile-first approach. No matter what device you're using, whether it's a smartphone, tablet, or desktop, you'll enjoy a seamless and intuitive user experience.
  2. Enhanced Accessibility: We understand the importance of accessing content from anywhere, at any time. The new Essential Evidence Plus will provide you with the flexibility to explore our extensive collection of evidence-based resources on the go, making it easier to stay up to date with the latest medical knowledge and interactive tools.
  3. Improved User Interface: We have revamped our user interface to ensure effortless navigation and a visually appealing experience. Finding the information, you need will be quicker and more intuitive, saving you valuable time and effort.

Essential Evidence Plus will be available to users during this transition. However, please note that ability to create new trial and individual subscriptions will not be available from September 8th to September 11th 7:00 AM EST. During this period, we will be working diligently to transfer our existing system to the upgraded platform, ensuring a seamless transition for all users.

We apologize for any inconvenience caused by this temporary interruption. Rest assured, our team is committed to bringing you a superior user experience, and we appreciate your patience and understanding during this time.

Stay Tuned for the New Essential Evidence Plus!

We are counting down the days until September 11th when the new Essential Evidence Plus will be available for you to explore. Get ready to unlock a wealth of evidence-based resources that empower you in your medical decision-making process.

Thank you for your continued support, and we look forward to delivering an exceptional experience with the all-new Essential Evidence Plus!

Essential Evidence Plus

Searching & Browsing: Databases Searched

Essential Evidence Plus searches 7 different databases. Select one of the databases listed below for a description of the database and its purpose, as well as an example of how it can be used in the clinical decision process.

These additional resources are also available:


Number Needed To Treat (NNT)

A statistic that conveys how many patients need to be treated with one intervention, instead of another, for one additional patient to receive benefit

Purpose: To help compare the likelihood of benefit (or harm) among several potential therapeutic options, since most interventions don’t benefit (or harm) 100% of the patients treated

Example of use: In the treatment of class I or II heart failure, treatment of 100 patients with an ACE inhibitor will prevent one additional death. In more severe disease (class IV), only six patients require treatment for an additional death to be prevented.

Detailed Description: The NNT gives us a better understanding of the relative benefit of treatment as compared with other statistics such as relative risk reduction. By knowing the NNT, clinicians and patients can determine whether a particular treatment is "worth it."